DNA/GENE MICROARRAY MARKET ANALYSIS

The global DNA/gene microarray market is estimated to be valued at US$ 4.24 Billion in 2023 and is expected to exhibit a CAGR of 12.9% during the forecast period (2023-2030).

Analysts’ Views on Global DNA/Gene Microarray Market:

• A rising number of growth strategies, such as partnerships and others, by the market players for DNA/gene microarray manufacturing and screening processes are expected to propel market growth over the forecast period. For instance, on July 18, 2023, Arrayjet, a leading provider of inkjet liquid-handling solutions, announced that it had entered into a partnership with Chemspace, an online catalog of small molecules and biologics, to augment and streamline the company’s small molecule microarray (SMM) service offering. Chemspace’s curated and deeply annotated compound libraries are now accessible through Arrayjet’s SMM Contract Research Organizations and Contract Manufacturing Organizations services for assay development, contract screening, and contract array manufacturing of DNA/gene.

Figure 1. Global DNA/Gene Microarray Market Share (%), By Type, 2023

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Global DNA/Gene Microarray Market– Drivers

• Rising strategic initiatives taken by the market players: The key market players are focused on strategic initiatives, which, in turn, are expected to fuel market growth over the forecast period. For instance, in March 2021, Oxford BioDynamics Plc, a global biotechnology company, and Agilent Technologies, a provider of scientific solutions, announced that they had signed a supply and resale agreement for the manufacturing and sale of the new EpiSwitch Explorer Array Kit. EpiSwitch Explorer Array Kit is a microarray kit available for high-resolution 3D (3-dimensional) genome profiling and biomarker discovery.

• Increasing prevalence of cancer: Increasing changes in lifestyles are considered a major cause of cancer. Thus, the increasing prevalence of cancer globally is expected to boost growth of the market over the forecast period, as arrays are used in diagnostics for various indications such as cancer and others. For instance, according to the data published by the American Cancer Society in 2021, cancer facts and figures in the U.S. reported the estimated number of cancer cases in the U.S. in 2021, which is provided below:

Figure 2. Global DNA/Gene Microarray Market Share (%), By Region, 2023

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Global DNA/Gene Microarray Market- Regional Analysis

• Among regions, North America is estimated to hold a dominant position in the global DNA/gene microarray market over the forecast period. North America is estimated to hold 33.5% of the market share in 2023. The global DNA/gene microarray market is expected to witness significant growth in the coming years, owing to increasing product launches by key market players. For instance, in March 2020, Agilent Technologies Inc. announced the launch of Agilent GenetiSure Cyto microarrays for prenatal and postnatal research. The new Agilent GenetiSure Cyto microarrays include updated, clinically relevant content from respected databases. The probes on the Cyto microarrays provide high-resolution detection of copy number variations and copy-neutral loss of heterozygosity associated with developmental delay, neuropsychiatric disorders, intellectual disability, congenital anomalies, or unexplained dysmorphic features in constitutional DNA samples.

Global DNA/Gene Microarray Market– Impact of Coronavirus (COVID-19) Pandemic

• Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe, and the World Health Organization declared it a public health emergency on January 30, 2020.
• COVID-19 affected the economy in three main ways: by directly affecting the production and demand of drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries, such as China, India, Saudi Arabia, the U.A.E., Egypt, and others, are facing problems with the transportation of things from one place to another.
• The COVID-19 pandemic had a positive impact on the global DNA/gene microarray market, owing to increased research and development activities using arrays in the treatment of patients suffering from COVID-19. For instance, in August 2020, according to the report published by Aurora Biomed Inc., a provider of lab automation solutions for life science, environmental science, drug discovery and safety, and chemical analysis research, microarrays, including DNA and RNA microarrays, etc., were all considered powerful tools in the ongoing research related to COVID-19. These microarrays can analyze hundreds or even thousands of samples in a single run, making them much faster than traditional virus detection methods. These techniques allow researchers to rapidly screen for the presence of viral proteins in samples, providing valuable information about the virus and its behavior.
• Furthermore, in January 2022, according to the published article titled "Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans", tissue microarrays incorporating a total of 879 tissue cores from conjunctiva (n = 84), sinonasal (n = 95), and lung (bronchiolar/alveolar; n = 96) specimens were investigated for protein expression by immunohistochemistry. The study confirms and extends previous findings and contributes to a better understanding of potential SARS-CoV-2 infection sites along the human respiratory tract. Such studies indicate significant demand for tissue microarray products amid the pandemic.

Estimated New Cancer Cases In The U.S In 2021

Global DNA/Gene Microarray Market Segmentation:

The global DNA/gene microarray market report is segmented into by type, by application, by end user and by region.

• By type, the market is segmented into oligonucleotide DNA microarrays and complementary DNA microarrays. Out of which, the oligonucleotide DNA microarrays segment is expected to hold a dominant position in the global DNA/gene microarray market during the forecast period, and this is attributed to the rising  prevalence of cancer cases globally.
• By application, the market is segmented into genomics, proteomics, agricultural biology, environment, drug research and development, cancer/oncology, and others (SNP analysis, etc.). Out of which, the genomics segment is expected to dominate the market over the forecast period, and this is attributed to the adoption of various growth strategies, such as product launches, partnership strategies, and others, by the market players.
• By end user, the market is segmented into biopharmaceutical and pharmaceutical companies, diagnostic laboratories, research laboratories, and others (academic institutes and others). The diagnostic laboratories segment is expected to dominate the market over the forecast period, and this is due to the increasing demand for diagnostic laboratories for the diagnosis of various diseases such as cancer and others.
• Based on region, the market is segmented into North America, Latin America. Europe, Asia Pacific, Middle East and Africa. Out of which, the North America region is expected to dominate the market over the forecast period, and this is due to the increasing product approval from the U.S FDA (Food and Drug Administration) by the market players in this region.
• Among all the segmentations, the type segment has the highest potential due to the increasing inorganic growth strategies, such as acquisitions and others, by the key market players. For instance, in September 2021, SCHOTT MINIFAB, a subsidiary of SCHOTT, a technology company that develops and manufactures microfluidic devices for point-of-care and life sciences consumables, announced that they had acquired Applied Microarrays Inc. (AMI), a U.S.-based company, which will further help the company strengthens its single-source contract manufacturing solution in the North America Region.

Global DNA/Gene Microarray Market- Cross Sectional Analysis:

The rising number of new product launches in the North America region, is expected to propel market growth over the forecast period. For instance, In April 2021, the National Center for Biotechnology Information announced the introduction of CovidArray, a microarray-based test to detect COVID-19 markers N1 and N2 in nasopharyngeal swab samples. The universal microarray can detect the genotypes of six mutated bases related to COVID-19.

Global DNA/Gene Microarray Market: Key Developments

• On January 15, 2023, National Center for Biotechnology Information, announced the development of a microarray system to detect UDP-glucuronosyltransferase gene polymorphisms for use in clinical laboratories in patients eligible for irinotecan hydrochloride treatment. It allows the construction of a measurement system for high-density and DNA fixation clinical applications.
• In November 2022, Sengenics, a precision medicine company, announced the commercial launch of dual-color IgG/IgA assay services. The new dual-color assays accelerate the pace and expand the biological space in the quest to discover new autoantibody biomarkers.
• In May 2022, Qatar Genome Program, a research institute, and Thermo Fisher Scientific, a provider of diagnostic solutions, announced a partnership to accelerate genomic research and clinical applications of predictive genomics in Qatar. This partnership expanded the advantages of precision medicine across the Middle East. Moreover, it comprises custom genotyping arrays designed to boost clinical applications of predictive genomics.
• In February 2021, 23andMe, a biotechnology company, announced it they had merged with VG Acquisition Corp., a bank investment company. This merger would provide capital funds for their genetic consumer health business and genetic research activities.

Global DNA/Gene Microarray Market: Key Trend

• Increasing fundings by the market players: Increasing growth strategies by the market players, such as funding and others, are expected to drive growth of the market over the forecast period. For instance, in June 2022, Ariceum Therapeutics, a private clinical-stage radiopharmaceutical company, announced funding of US$ 25 million in Series A to enhance its lead asset, Satoreotide, for the diagnosis of low- and high-neuroendocrine cancer.

Global DNA/Gene Microarray Market: Restraint

• High cost of Microarray Sequencing: The manufacturing complexity of the biochip technology and the research and development that is required to bring out innovative biochips to market result in high costs for these products, while the high cost involved in research and development of DNA/gene microarray technology-based products and limited financial support have posed a great challenge to the growth of the global DNA/Gene microarray market. The high cost of DNA microarray sequencing used in various applications, such as cancer and others, is further expected to hinder market growth over the forecast period. For instance, in June 2022, according to the report published in the National Center for Biotechnology Information, the reported price of DNA microarrays used in cancer diagnostics ranged from US$ 335 to US$ 700. To overcome this high cost, the government has given reimbursement policies that patients must opt for to avail of a proper discount and avoid out-of-pocket expenses.

Global DNA/Gene Microarray Market - Key Players

Major players operating in the global DNA/gene microarray market include Affymetrix, Inc., Illumina, Inc., Agilent Technologies Inc., Roche NimbleGen Inc., Sequenom, Inc., Biometrix Technology Inc., LC Sciences, Life Technologies Corp., Lifegen Technologies LLC, Microarrays Inc., Thermo Fisher Scientific Inc., Bio-Rad Laboratories, Inc., Caliper Life Sciences, Perkin Elmer, Inc., PathogenDx, Inc., Twist Bioscience Corporation, Arraylt Corporation, Molecular Device, LLC and Raybiotech Inc.

*Definition: A DNA microarray or chip is a semiconductor surface on which sequences of many varied genes are bonded to probes. DNA microarrays are used to quantify the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. The approach finds application in drug R&D, clinical diagnosis, agriculture, environmental control, and other sectors. A microarray or biochip is a lab-oriented microscope slide that is usually made of glass, a silicon chip, or a nylon membrane. It is a 2D array (sometimes 3D) whose surface is provided with thousands of minute pores in defined positions.