Protein Expression Systems Market, By Expression System (Mammalian Expression Systems, Insect Expression Systems, Bacterial Expression Systems, Plant Expression Systems, Yeast Expression Systems, and Cell Free Expression Systems), By Product Type (Competent Cells, Instruments, Reagents, and Others), By Application (Protein Therapeutics, and Research Studies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2018-2026

  • Published On : Dec 2018 |
  • Pages : 164 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Protein Expression Systems Market – Insights

Protein expression has become an important laboratory technology in biochemistry, molecular biology, and protein research as well as other scientific research fields, which require functional proteins for their research. The technology can also provide substrates or enzymes required for further analysis. Many chemically competent bacterial cells such as E. coli cells, suitable for protein expression and transformation, are available as research kits. Other commonly used protein expression systems include cell systems derived from insect, plants, yeast, and mammalian cells.

The global protein expression systems market size was valued at US$ 1.2 billion in 2017, and is expected to witness a CAGR of 11.1% over the forecast period (2018 – 2026).

Global Protein Expression Systems Market Revenue (US$ Mn) Analysis, By Expression Systems, 2017

Source: Coherent Market Insights Analysis (2018)

Increasing demand for protein therapeutics is expected to drive the protein expression systems market revenue

Rising incidence of various diseases such as cancer, cardiovascular conditions, and genetic disorders is the major factor driving growth of protein expression system market. For instance, protein-based drugs such as insulin, can treat a wide variety of conditions with remarkable effectiveness. Moreover, high efficiency of protein therapeutics and minimum risk of side effects associated with protein therapeutics is attracting manufacturers to invest in the protein expression systems research and development. Recombinant proteins such as enzymes and biologics are useful in the biopharmaceutical, chemical, and food industries.

Furthermore, advances in protein-engineering technologies allow drug developers and manufacturers to modify and develop desirable functional characteristics of proteins of interest while maintaining product efficacy and safety. For instance, in 2017, HumanZyme Inc., a leading supplier of novel recombinant human proteins and growth factors expressed in human cells, announced the launch of HumanKine(r) Interferon gamma (IFN gamma) expressed from HEK293 cells. IFN gamma protects against bacterial, viral, and protozoan infections.

Protein Expression Systems Market Restraints

Despite tremendous application of protein therapeutics in R&D and drug development, in some cases, the production of recombinant proteins can be expensive, complex, and time-consuming. Moreover, the recombinant proteins produced in cells may not be the same as the natural forms, therefore the difference can reduce effectiveness of therapeutic recombinant proteins and even cause side effects.

Protein Expression Systems Market - Regional Insights

On the basis of region, the global protein expression systems market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America protein expression systems market is expected to generate significant revenue share during the forecast period, owing to increasing biopharmaceutical research and development investment and activities from public and private organizations. For instance, according to Pharmaceutical Research and Manufacturers of America (PhRMA), 2016, member companies invested around US$ 58.8 billion in research and development in 2015, of which, majority was by all biopharmaceutical companies in the U.S.

Asia Pacific protein expression systems market is anticipated to grow at highest CAGR during the forecast period. The lucrative growth in the region is majorly attributed to rising interests of regional manufacturers in protein therapeutics. For instance, in 2016, Takeda Pharmaceutical and Crescendo Biologics collaborated and license agreement for the discovery, development and commercialization of Humabody-based therapeutics for cancers with a high unmet medical need. Humabodies are a novel class of extremely small, robust, and potent protein therapeutics.

Global Protein Expression Systems Market Value (US$ Mn) & Y-o-Y Growth (%)

   

 Source: Coherent Market Insights Analysis (2018)

Protein Expression Systems Market - Competitive Landscape

Key players operating in the global protein expression systems market include Agilent Technologies, Inc., Becton, Dickinson & Company, Lonza Group Ltd., GenScript Biotech Corporation, Bio-Rad Laboratories, Inc., Merck KGaA, QIAGEN N.V., Thermo Fisher Scientific Inc., Takara Bio Inc., Synthetic Genomics Inc., Lucigen Corporation, Promega Corporation, ARTES Biotechnology GmbH, ProteoGenix, Addgene Inc., Geneva Biotech, Profacgen, and Peak Proteins Ltd.

Protein expression is an integral tool in biological research and it is gaining significant traction as a pharmaceutical production mechanism for biological therapeutics. The biotechnology industry uses both cell types prokaryotic (bacteria) and eukaryotic (animal, fungi, and plant) to synthesize recombinant proteins. The choice of the host cell depends on the protein expressed. The demand for recombinant proteins has increased as more applications in several fields are commercially available. Recombinant proteins have been utilized as tools for cellular and molecular biology.

Market Dynamics

The demand for protein therapeutics has increased considerably, owing to increase in prevalence of chronic diseases and development of plasma-derived therapies. In recent years, proteins expression systems have gained significant traction for therapeutic applications and the number of proteins launched or approved into clinical trials has continually increased. According to the National Center for Biotechnology Information (NCBI) data of 2017, the U.S. Food and Drug Administration (FDA) approved more than 140 recombinant therapeutic proteins for human use and several hundred are currently in development.

However, high cost associated with therapeutic proteins and stringent government regulations towards approval of protein therapies are expected to hinder market growth. For instance, in India, a vial of Avastin (Bevacizumab mostly produced by the mammalian cell expression system), a monoclonal antibody, cost between US$ 372.65 to US$ 402.46. Moreover, immunogenicity is also a major concern for all recombinant drugs, as all biotechnologically produced therapeutics may exhibit some form of immunogenicity.

Key features of the study:

  • This report provides in-depth analysis of the protein expression systems market, market size (US$ Mn), and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2018 – 2026, considering 2017, as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles key players in the global protein expression systems market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include Agilent Technologies, Inc., Becton, Dickinson & Company, Lonza Group Ltd., GenScript Biotech Corporation, Bio-Rad Laboratories, Inc., Merck KGaA, QIAGEN N.V., Thermo Fisher Scientific Inc., Takara Bio Inc., Synthetic Genomics Inc., Lucigen Corporation, Promega Corporation, ARTES Biotechnology GmbH, ProteoGenix, Addgene Inc., Geneva Biotech, Profacgen, and Peak Proteins Ltd.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, governmental initiatives, technological up-gradation, market expansion, and marketing tactics
  • The global protein expression systems market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors, and suppliers for protein expression systems market, research and consulting firms, new entrants, and financial analysts

Detailed Segmentation:

  • Global Protein Expression Systems Market, By Expression System:
    • Mammalian Expression Systems
    • Insect Expression Systems
    • Bacterial Expression Systems
    • Plant Expression Systems
    • Yeast Expression Systems
    • Cell Free Expression Systems
  • Global Protein Expression Systems Market, By Product Type:
    • Competent Cells
    • Instruments
    • Reagents
    • Others
  • Global Protein Expression Systems Market, By Application:
    • Protein Therapeutics
    • Research Studies
  • Global Protein Expression Systems Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Expression System:
        • Mammalian Expression Systems
        • Insect Expression Systems
        • Bacterial Expression Systems
        • Plant Expression Systems
        • Yeast Expression Systems
        • Cell Free Expression Systems
      • By Product Type:
        • Competent Cells
        • Instruments
        • Reagents
        • Others
      • By Application:
        • Protein Therapeutics
        • Research Studies
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Expression System:
        • Mammalian Expression Systems
        • Insect Expression Systems
        • Bacterial Expression Systems
        • Plant Expression Systems
        • Yeast Expression Systems
        • Cell Free Expression Systems
      • By Product Type:
        • Competent Cells
        • Instruments
        • Reagents
        • Others
      • By Application:
        • Protein Therapeutics
        • Research Studies
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
      • By Expression System:
        • Mammalian Expression Systems
        • Insect Expression Systems
        • Bacterial Expression Systems
        • Plant Expression Systems
        • Yeast Expression Systems
        • Cell Free Expression Systems
      • By Product Type:
        • Competent Cells
        • Instruments
        • Reagents
        • Others
      • By Application:
        • Protein Therapeutics
        • Research Studies
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Expression System:
        • Mammalian Expression Systems
        • Insect Expression Systems
        • Bacterial Expression Systems
        • Plant Expression Systems
        • Yeast Expression Systems
        • Cell Free Expression Systems
      • By Product Type:
        • Competent Cells
        • Instruments
        • Reagents
        • Others
      • By Application:
        • Protein Therapeutics
        • Research Studies
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Expression System:
        • Mammalian Expression Systems
        • Insect Expression Systems
        • Bacterial Expression Systems
        • Plant Expression Systems
        • Yeast Expression Systems
        • Cell Free Expression Systems
      • By Product Type:
        • Competent Cells
        • Instruments
        • Reagents
        • Others
      • By Application:
        • Protein Therapeutics
        • Research Studies
    • Africa
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
      • By Expression System:
        • Mammalian Expression Systems
        • Insect Expression Systems
        • Bacterial Expression Systems
        • Plant Expression Systems
        • Yeast Expression Systems
        • Cell Free Expression Systems
      • By Product Type:
        • Competent Cells
        • Instruments
        • Reagents
        • Others
      • By Application:
        • Protein Therapeutics
        • Research Studies
  • Company Profiles
    • Agilent Technologies, Inc.*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Becton, Dickinson & Company
    • Lonza Group Ltd.
    • GenScript Biotech Corporation
    • Bio-Rad Laboratories, Inc.
    • Merck KGaA
    • QIAGEN N.V.
    • Thermo Fisher Scientific Inc.
    • Takara Bio Inc.
    • Synthetic Genomics Inc.
    • Lucigen Corporation

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Expression System
      • Market Snippet, By Product Type
      • Market Snippet, By Application
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Technological Advancements
    • Regulatory Landscape
    • New Product Launches/Approvals
    • Research and Development Activities
    • PEST Analysis
  4. Global Protein Expression Systems Market, By Expression System, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Mammalian Expression Systems
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Insect Expression Systems
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Bacterial Expression Systems
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Plant Expression Systems
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Yeast Expression Systems
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Cell Free Expression Systems
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  5. Global Protein Expression Systems Market, By Product Type, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Competent Cells
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Instruments
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Reagents
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  6. Global Protein Expression Systems Market, By Application, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Protein Therapeutics
      •  Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
    • Research Studies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 – 2026, (US$ Million)
  7. Global Protein Expression Systems Market, By Region, 2018 – 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, By Region, 2018 – 2026
      • Regional Trends
    • North America
      • Market Size and Forecast, By Expression System, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Expression System, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Expression System, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Expression System, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Expression System, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • North Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Expression System, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Product Type, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Application, 2018 – 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2018 – 2026, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Agilent Technologies, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Becton, Dickinson & Company
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Lonza Group Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • GenScript Biotech Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Bio-Rad Laboratories, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Merck KGaA
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • QIAGEN N.V.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Thermo Fisher Scientific Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Takara Bio Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Synthetic Genomics Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Lucigen Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Promega Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • ARTES Biotechnology GmbH
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • ProteoGenix
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Addgene Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Geneva Biotech
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Profacgen
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Peak Proteins Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
  9. Analyst Views
  10. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 25 market data tables and 27 figures on "Protein Expression Systems Market” - Global forecast to 2026”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Smiley face

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Smiley face

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Choose License Type

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

[email protected]

Key Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.