Biotechnology

The biotech industry includes bio-pharma, bio-services, bio-agri, bio-industrials and bioinformatics. Biopharma is a rapidly growing segment that accounts for a dominant share in this sector. Advancements in biotechnology have enabled researchers to evaluate and identify target biomarkers/cell receptors to develop targeted and personalized therapies. Scientific research and technological advancements have resulted in the emergence of various personalized medicines that are undergoing research. According to research conducted by the Personalized Medicine Coalition, 42% of all compounds and 73% of oncology compounds in the pipeline possess the potential to be personalized medicine. Moreover, according to this study, it is expected that companies will increase their investment in R&D of personalized medicines by 1/3rd over the following five years. The study found that over 20% of drugs approved in 2014 were personalized medicines.

The biotechnology sector has witnessed some disruptive innovations such as gene and cell therapies, immunotherapy, and antibody drug conjugates. Advancement in stem cell therapy is resulting in effective treatment therapies for chronic conditions, organ growth and repair and disease prevention.

Key Challenges

Biotech products have extensive application in oncology and autoimmune disease treatment. However, the cost of these drugs is high owing to extensive research and trials that need to be carried out for the same. Therefore, there is constant pressure to reduce price and increase accessibility, especially in emerging economies. In the U.S., companies are facing reimbursement issues with respect to biopharmaceutical products. Besides, there are regulatory and scientific challenges faced by the sector. Scientific research for new molecules and targeted therapies is capital intensive and challenging owing to growing concern for safety of the drug.

Also, there is lack of awareness about personalized medicine among most healthcare providers, which may hamper its adoption. Clinical adoption of biotechnology products is essential for its success. However, it significant scientific evidence and backing is required to ensure its safety.

“Translating genomic discoveries into personalized medicines entails overcoming substantial scientific, regulatory, and economic challenges, including identifying validated biomarkers, as well as developing personalized therapeutics and clinically relevant diagnostic tests.”

  • Tufts Center for the Study of Drug Development

Opportunities

The biopharmaceutical sector offers vast lucrative growth opportunities. High efficacy and safety of biopharmaceutical products has led to a growth in their demand, Furthermore, consumers are willing to pay high prices for biopharmaceutical products compared to other conventional products. Biopharmaceutical brands have set new standards for blockbuster drugs by recording an annual average sale of over US$ 2bn. Drugs such as Humira have generated sales revenue of over US$ 10bn.

Governments in emerging economies are endorsing biosimilars as cost-effective alternatives to biotech products, which is expected to create significant growth opportunities for manufacturers of generic drugs. Therefore, cost-effectiveness and high quality are prime parameters that need to be considered while developing biosimilars. Recent and upcoming biologic patent expirations include the following:

  • Erbitux (cetuximab) - February 2016
  • Rituxan (rituximab) - September 2016
  • Herceptin (trastuzumab) - June 2019
  • Avastin (bevacizumab) - July 2019
  • Aranesp (darbepoetin alfa) - May 2024
  • Enbrel (etanercept) - November 2028

Companies such as Teva Pharmaceuticals, Hospira, Sandoz, and Amgen are focusing on development of biosimilars and vaccines as preventive measures in addition to treatment. For instance, in 2015, Zarxio TM became the first biosimilar to be approved in the U.S. market. The EMA approved Mosquirix, a malaria vaccine, in the same year. Extensive research is currently underway to develop a dengue vaccine, which could be another breakthrough pharmaceutical product in the near future.

Conclusion

The increasing research in the biotechnology sector is expected to result in higher number of biopharmaceutical products seeking FDA approvals. Biopharmaceuticals are positioned to be promising treatment solutions that would improve patient outcomes and help with reduction of the cost of drug development.

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Biotechnology Published Insights

Coherent Market Insights Flow Imaging Microscopy Analysis Market

Published Date : Nov 2023

Flow imaging microscopy analysis is a revolutionary technique that allows for the visualization and analysis of particles in a fluid sample. This technology offers a unique perspective on particle characterization, providing valuable insights for a wide range of appli... View more

Coherent Market Insights Bioengineered Artificial Skin Market

Published Date : Nov 2023

Bioengineered skin is designed to undertake the functions of the epidermis and/or dermis as a temporary usage till the patient's skin barrier spontaneously repairs itself naturally. Bioengineered skin is used to address severe scars which represents the result of the ... View more

Coherent Market Insights Marine Biotechnology Market

Published Date : Nov 2023

Marine biotechnology is the creation of products and processes from marine organisms through the application of biotechnology, molecular and cell biology, and bioinformatics. It is the field of science that deals with ocean exploration for development of new pharmaceutical drugs, chemical product... View more

Coherent Market Insights Vaccine Technologies Market

Published Date : Nov 2023

Vaccine technology refers to the methods and strategies used to create vaccines. Vaccines are biological substances that can improve immunity to a particular disease. They prepare the body's immune system to fight off specific infections. Vaccine technologies have wit... View more

Coherent Market Insights Humira Biosimilar Market

Published Date : Nov 2023

Humira is a biologic medication used to treat autoimmune conditions like psoriasis and rheumatoid arthritis and is the most popular biologic medication in the world. Following the expiration of patent protection for humira in some regions, biosimilars are highly simil... View more

Coherent Market Insights Lyophilization Services For Biopharmaceuticals Market

Published Date : Oct 2023

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Coherent Market Insights Occupational Health Market

Published Date : Oct 2023

As organizations strive to create a safe and healthy work environment, the global occupational health market is expected to witness substantial growth in the coming years. Factors such as stringent government regulations, increasing awareness about occupational health... View more

Coherent Market Insights Electrocompetent Cells Market

Published Date : Oct 2023

Electrocompetent cells are bacterial cells that have been prepared for the uptake of DNA through electroporation, a process that involves exposing the cells to an electric field that creates temporary pores in the cell membranes. This allows foreign DNA to enter the c... View more

Coherent Market Insights Neutralizing Antibody Market

Published Date : Oct 2023

Neutralizing antibodies are a critical component of natural immunity and can be induced by both natural infection and vaccination. These antibodies recognize specific parts of the virus and prevent them from binding to and infecting cells. The antibodies’ specia... View more

Coherent Market Insights Bioprocess Validation Market

Published Date : Oct 2023

Bioprocess validation is the collection and evaluation of data, from the design stage through commercial production, which establishes scientific evidence that a process is capable of consistently delivering quality product. It is a regulatory requirement for biopharm... View more

Coherent Market Insights Personalized Genomics Market

Published Date : Oct 2023

Personalized genomics is a rapidly growing field that combines genetics, genomics, and personalized medicine to provide individuals with valuable insights into their genetic makeup. Market Dynamics:    &... View more

Coherent Market Insights Tumor Microenvironment Market

Published Date : Oct 2023

The tumor microenvironment is a complex ecosystem consisting of various cellular and non-cellular components that interact with each other and play a crucial role in tumor development and progression. These components include immune cells, fibroblasts, blood vessels, ... View more

Coherent Market Insights Us Acellular Dermal Matrices Market

Published Date : Oct 2023

Acellular dermal matrices are generated by decellularization process, which leads to the removal of the cells and preserving of the extracellular matrix. The extracellular matrix ones implanted in the required area, serves as the scaffold for the donor cells. The dono... View more

Coherent Market Insights Amniotic Membrane Market

Published Date : Oct 2023

Amniotic membrane is an avascular layer of fetal membrane which can be extracted from placenta and stored in a sterile environment right after collection. It can be efficiently used in surgical procedures and in the treatment of ocular diseases or disorders such as li... View more

Coherent Market Insights Oligonucleotide Synthesis Market

Published Date : Oct 2023

Oligonucleotides are commonly used as primers for polymerase chain reaction (PCR), PCR assays, and panels for biologically related genes. Antisense oligonucleotides are used to reduce levels of protein synthesis by inhibiting mRNA processing or translation. Other uses... View more

Coherent Market Insights South East Asia And South Asia Industrial Microbiology Market

Published Date : Oct 2023

Industrial microbiology apply the use of microorganisms in manufacturing of food or industrial products in bulk quantities. Thousands of microorganisms are utilised within industrial microbiology field. Some of these microorganisms include naturally occurring organism... View more

Coherent Market Insights Plant Based Vaccines Market

Published Date : Oct 2023

Plants are a cost-effective, safe, and efficacious platform for large-scale production of vaccine in emerging economies. Key players in the market are focused on Research & Development (R&D) activities for development of plant-based vaccines for the treatment ... View more

Coherent Market Insights Acellular Dermal Matrices Market

Published Date : Oct 2023

Acellular dermal matrices are generated by decellularization process, which leads to the removal of the cells and preserving of the extracellular matrix. The extracellular matrix ones implanted in the required area, serves as the scaffold for the donor cells. The dono... View more

Coherent Market Insights Orthopedic Regenerative Medicine Market

Published Date : Oct 2023

Orthopedic regenerative medicine are therapies developed from biologic (natural) substances that can be used by orthopaedic specialists to: Help relieve pain and other symptoms of certain orthopaedic conditions, such as early osteoarthritis, which may help delay the n... View more

Coherent Market Insights Mena Biologics And Biosimilars Market

Published Date : Sep 2023

A biologic drug (biologics) is a product that is produced from living organisms or contains components of living organisms. New technologies for manufacturing of biologics, which hold potential for the MENA biologics & ... View more

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