Sales Support
sales@coherentmarketinsights.comUS.: +1-206-701-6702
UK.: +44-020-8133-4027
JAPAN: +81-50-5539-1737
INDIA: +91-848-285-0837
The biotech industry includes bio-pharma, bio-services, bio-agri, bio-industrials and bioinformatics. Biopharma is a rapidly growing segment that accounts for a dominant share in this sector. Advancements in biotechnology have enabled researchers to evaluate and identify target biomarkers/cell receptors to develop targeted and personalized therapies. Scientific research and technological advancements have resulted in the emergence of various personalized medicines that are undergoing research. According to research conducted by the Personalized Medicine Coalition, 42% of all compounds and 73% of oncology compounds in the pipeline possess the potential to be personalized medicine. Moreover, according to this study, it is expected that companies will increase their investment in R&D of personalized medicines by 1/3rd over the following five years. The study found that over 20% of drugs approved in 2014 were personalized medicines.
The biotechnology sector has witnessed some disruptive innovations such as gene and cell therapies, immunotherapy, and antibody drug conjugates. Advancement in stem cell therapy is resulting in effective treatment therapies for chronic conditions, organ growth and repair and disease prevention.
Key Challenges
Biotech products have extensive application in oncology and autoimmune disease treatment. However, the cost of these drugs is high owing to extensive research and trials that need to be carried out for the same. Therefore, there is constant pressure to reduce price and increase accessibility, especially in emerging economies. In the U.S., companies are facing reimbursement issues with respect to biopharmaceutical products. Besides, there are regulatory and scientific challenges faced by the sector. Scientific research for new molecules and targeted therapies is capital intensive and challenging owing to growing concern for safety of the drug.
Also, there is lack of awareness about personalized medicine among most healthcare providers, which may hamper its adoption. Clinical adoption of biotechnology products is essential for its success. However, it significant scientific evidence and backing is required to ensure its safety.
“Translating genomic discoveries into personalized medicines entails overcoming substantial scientific, regulatory, and economic challenges, including identifying validated biomarkers, as well as developing personalized therapeutics and clinically relevant diagnostic tests.”
Opportunities
The biopharmaceutical sector offers vast lucrative growth opportunities. High efficacy and safety of biopharmaceutical products has led to a growth in their demand, Furthermore, consumers are willing to pay high prices for biopharmaceutical products compared to other conventional products. Biopharmaceutical brands have set new standards for blockbuster drugs by recording an annual average sale of over US$ 2bn. Drugs such as Humira have generated sales revenue of over US$ 10bn.
Governments in emerging economies are endorsing biosimilars as cost-effective alternatives to biotech products, which is expected to create significant growth opportunities for manufacturers of generic drugs. Therefore, cost-effectiveness and high quality are prime parameters that need to be considered while developing biosimilars. Recent and upcoming biologic patent expirations include the following:
Companies such as Teva Pharmaceuticals, Hospira, Sandoz, and Amgen are focusing on development of biosimilars and vaccines as preventive measures in addition to treatment. For instance, in 2015, Zarxio TM became the first biosimilar to be approved in the U.S. market. The EMA approved Mosquirix, a malaria vaccine, in the same year. Extensive research is currently underway to develop a dengue vaccine, which could be another breakthrough pharmaceutical product in the near future.
Conclusion
The increasing research in the biotechnology sector is expected to result in higher number of biopharmaceutical products seeking FDA approvals. Biopharmaceuticals are positioned to be promising treatment solutions that would improve patient outcomes and help with reduction of the cost of drug development.
Published Date : Nov 2021
Cardiac biomarkers are substances that are released into the blood when the heart is damaged or stressed. Measurements of these biomarkers are used to help diagnose acute cor... View more
Published Date : Oct 2021
Ataxia refers to a group of degenerative neurological diseases that affect coordination and movement center of the brain (cerebellum). People suffering from ataxia have difficulty in swallowing, speech, and maintaining balance or coordination. Ataxia can be classified... View more
Published Date : Sep 2021
Bovine serum albumin (BSA) is protein derived from cows. Bovine serum albumin has negative charge, which binds salts, water, fatty acid, vitamins, and hormones and carries these attached materials between tissues and cells. BSA offers features such as sensitivity, com... View more
Published Date : Sep 2021
COVID-19 infection is caused by SARS-CoV-2, which is a highly transmissible and life-threatening strain of coronavirus. Nasal swab is a method used for collecting clinical test samples of nasal secretions. Nasal swabs can be used for analysis of number of infectious d... View more
Published Date : Aug 2021
Diabetes, also known as Diabetes mellitus is a condition, wherein the concentration of glucose increases in the blood due to shortage of insulin or insulin resistance. Some of the commonly experienced symptoms of diabetes include increased thirst, frequent urination, ... View more
Published Date : Aug 2021
Cytology refers to the microscopic examination of both plant and animal cell samples with regards to their structure, chemical composition, and function. The examination of cells can be carried out through various methods such as scraping the tissue surface, collectio... View more
Published Date : Aug 2021
Phenotype refers to the physical characteristics of an organism that can be observed and measured. Interactions between alleles of an organism gives rise to different combinations of phenotypes such as morphology, biochemical properties, etc. Gregor Mendel, also known... View more
Published Date : Aug 2021
Neurological biomarkers are biological indicators present in the cerebrospinal fluid that can be measured to study the health of the brain. Neurological biomarkers can be of various types such as imaging biomarkers, metabolomics biomarkers, proteomic biomarkers, and g... View more
Published Date : Aug 2021
Antifreeze proteins are peptides or polypeptides produced by certain organisms that lower the freezing point of water to prevent crystallization in the frozen state. This allows organisms to survive at a temperature below zero degree Celsius without any freezing damag... View more
Published Date : Aug 2021
Genomic biomarkers are either DNA or RNA characteristics that are associated with a physiological process, immunological process or therapeutic response. A genomic biomarker reveals the expression, function, and regulation of a gene. DNA characteristics that act as ge... View more
Published Date : Aug 2021
Blood is a specialized bodily fluid that circulates through the entire body with the help of a network of blood vessels such as arteries, veins, and capillaries. Blood is made up of four major components, which include red blood cells, white blood cells, plasma, and p... View more
Published Date : Jul 2021
Gene panels are specialized diagnostic tools used to assess multiple genes at once for mutations related to diseases such as cancer, cardiomyopathy, and others. Gene panels enable the users to obtain results at a reduced cost and time. Gene panels are useful in s... View more
Published Date : Feb 2021
Regenerative medicine is a biological heterogeneous domain that incorporates material science, engineering, medicine, biological science, and surgery. It acts therapeutically by augmenting and stimulating the body’s capacity for regeneration and self-repair. Reg... View more
Published Date : Dec 2020
Transplantation is a complex area of medicine because when organs or tissues are transplanted from one person to another, the recipient’s immune system can reject and destroy the donor organ or tissue and medication would be needed to suppress this immune respon... View more
Published Date : Nov 2020
Plant-based biologics are biologic drugs that are manufactured by using plant molecular farming. They are also known as plant-made biologics (PMB). The applications and advantages of plant-based biologics have stretched beyond the traditional boundaries of vaccines an... View more
Published Date : Aug 2020
Genomics is the study of human genes and chromosomes. It focuses on structure, function, evolution, mapping, and editing of genomes. Genome is the genetic material of organism, which includes the Deoxyribonucleic acid (DNA). DNA consists the information needed to buil... View more
Published Date : Aug 2020
Allogeneic human chondrocyte cell therapy is anticipated to be a good alternative to autologous chondrocyte implantation in the near future. Increasing product approvals by regulatory authorities is expected to fuel the market growth over the forecast period. For inst... View more
Published Date : Jul 2020
Transcriptomics the study of structures and functions of transcript molecules. Transcripts comprise all types of ribonucleic acid (RNA) molecules namely, messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), and other non-coding RNA molecules. Increasing ap... View more
Published Date : May 2020
White Biotechnology refers to the adoption of biotechnology in developing methods to replace petroleum-based synthetics. Major application of white biotechnology constitutes in the production of biochemical, biofuels, and biomaterials. Butanediol, lactic acid, succini... View more
Published Date : May 2020
Meningitis is an inflammation in the inner lining of the brain and spinal cord that results from infectious (viral, bacterial, and rarely fungal) or non-infectious (drugs, sarcoidosis etc.) factors. The swelling associated with meninges triggers symptoms such as painf... View more